MoG+ -Mouse Genome database with high added value-

Target CDS Information

Gene Symbol (Gene ID)

Pklr (ENSMUSG00000041237)

Cross Reference

EMBL	AC161600
GO	GO:0000287, GO:0004743, GO:0006096, ...show all
goslim_goa	GO:0003674, GO:0005575, GO:0005576, ...show all
MGI_trans_name	Pklr-003
OTTP	OTTMUSP00000019091
OTTT	OTTMUST00000042491
Reactome	R-MMU-1430728, R-MMU-70171, R-MMU-70326, ...show all
UniParc	UPI0000DBED38
Uniprot/SPTREMBL	D3Z2C4
Vega_transcript	OTTMUST00000042491, Pklr-003

Vega_translation

187643, OTTMUSP00000019091

Definition

protein_id:ENSMUSP00000119392
translation:

MADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSH
EYHAESIANIRE

Chromosome

Length
Position(start - end)

4,222
89,137,316 - 89,141,539

Orient to Chromosome

plus

Link

Location : (3:89137316-89141539)
/

Detail Map

name	Pklr (ENSMUSG00000041237)
type	gene
link	VEGA Ensembl MGI
xref
definition	locus_tag : Pklr note : pyruvate kinase liver and red blood cell [Source:MGI Symbol;Acc:MGI:97604]

name	Pklr (ENSMUSG00000041237)
type	mRNA
link	VEGA Ensembl MGI
xref
definition	note : transcript_id=ENSMUST00000047111

name	Pklr (ENSMUSG00000041237)
type	mRNA
link	VEGA Ensembl MGI
xref
definition	note : transcript_id=ENSMUST00000107482

name	Pklr (ENSMUSG00000041237)
type	mRNA
link	VEGA Ensembl MGI
xref
definition	note : transcript_id=ENSMUST00000127058

name	Pklr (ENSMUSG00000041237) (Detail)
type	CDS
link	VEGA Ensembl MGI
xref	CCDS:CCDS17489.1 RefSeq_peptide:NP_038659 RefSeq_mRNA:NM_013631.2 Vega_transcript:OTTMUST00000042489 Vega_transcript:Pklr-001 Uniprot/SPTREMBL:G3X925 UCSC:uc008pxp.1 EMBL:AC161600 EMBL:CH466547 GO:GO:0000287 GO:GO:0001666 GO:GO:0004743 GO:GO:0004743 GO:GO:0005829 GO:GO:0005975 GO:GO:0006096 GO:GO:0006754 GO:GO:0007584 GO:GO:0009408 GO:GO:0009749 GO:GO:0010038 GO:GO:0010226 GO:GO:0014070 GO:GO:0030955 GO:GO:0032869 GO:GO:0033198 GO:GO:0042866 GO:GO:0051591 GO:GO:0051707 GO:GO:0070062 GO:GO:0070062 MGI_trans_name:Pklr-001 Vega_translation:187641 Vega_translation:OTTMUSP00000019089 goslim_goa:GO:0003674 goslim_goa:GO:0005575 goslim_goa:GO:0005576 goslim_goa:GO:0005975 goslim_goa:GO:0006091 goslim_goa:GO:0008150 goslim_goa:GO:0009056 goslim_goa:GO:0034641 goslim_goa:GO:0043167 goslim_goa:GO:0043226 goslim_goa:GO:0044281 goslim_goa:GO:0051186 protein_id:EDL15236.1 OTTP:OTTMUSP00000019089 OTTT:OTTMUST00000042489 Reactome:R-MMU-1430728 Reactome:R-MMU-70171 Reactome:R-MMU-70326 Reactome:R-MMU-71387 UniParc:UPI00000266A1
definition	note : transcript_id=ENSMUST00000047111 protein_id : ENSMUSP00000035417 translation : MSVQENELPQQLWPWIFKSQKDLAKSALSGAPGGPAGYLRRASVAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREAAESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFRTRGDAKTVWVDYHNITQVVAVGGRIYIDDGLISLVVRKIGPEGLVTEVEHGGFLGNRKGVNLPNAEVDLPGLSEQDLLDLRFGVEHNVDIIFASFVRKASDVVAVRDALGPEGRGIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPEAVWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLTIS

name	Pklr (ENSMUSG00000041237) (Detail)
type	CDS
link	VEGA Ensembl MGI
xref	CCDS:CCDS50957.1 RefSeq_peptide:NP_001093249 RefSeq_mRNA:NM_001099779.1 RefSeq_mRNA_predicted:XM_006501134.2 RefSeq_mRNA_predicted:XM_006501135.2 RefSeq_peptide_predicted:XP_006501197.1 RefSeq_peptide_predicted:XP_006501198.1 Vega_transcript:OTTMUST00000042490 Vega_transcript:Pklr-002 Uniprot/SPTREMBL:E9Q509 UCSC:uc008pxq.1 EMBL:AC161600 GO:GO:0000287 GO:GO:0004743 GO:GO:0006096 GO:GO:0030955 GO:GO:0051707 GO:GO:0070062 MGI_trans_name:Pklr-002 Vega_translation:187642 Vega_translation:OTTMUSP00000019090 goslim_goa:GO:0003674 goslim_goa:GO:0005575 goslim_goa:GO:0005576 goslim_goa:GO:0005975 goslim_goa:GO:0006091 goslim_goa:GO:0008150 goslim_goa:GO:0009056 goslim_goa:GO:0034641 goslim_goa:GO:0043167 goslim_goa:GO:0043226 goslim_goa:GO:0044281 goslim_goa:GO:0051186 OTTP:OTTMUSP00000019090 OTTT:OTTMUST00000042490 Reactome:R-MMU-1430728 Reactome:R-MMU-70171 Reactome:R-MMU-70326 Reactome:R-MMU-71387 UniParc:UPI0000DBED37
definition	note : transcript_id=ENSMUST00000107482 protein_id : ENSMUSP00000103106 translation : MEGPAGYLRRASVAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREAAESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFRTRGDAKTVWVDYHNITQVVAVGGRIYIDDGLISLVVRKIGPEGLVTEVEHGGFLGNRKGVNLPNAEVDLPGLSEQDLLDLRFGVEHNVDIIFASFVRKASDVVAVRDALGPEGRGIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPEAVWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLTIS

name	Pklr (ENSMUSG00000041237) (Detail)
type	CDS
link	VEGA Ensembl MGI
xref	Vega_transcript:OTTMUST00000042491 Vega_transcript:Pklr-003 Uniprot/SPTREMBL:D3Z2C4 EMBL:AC161600 GO:GO:0000287 GO:GO:0004743 GO:GO:0006096 GO:GO:0030955 GO:GO:0051707 GO:GO:0070062 MGI_trans_name:Pklr-003 Vega_translation:187643 Vega_translation:OTTMUSP00000019091 goslim_goa:GO:0003674 goslim_goa:GO:0005575 goslim_goa:GO:0005576 goslim_goa:GO:0005975 goslim_goa:GO:0006091 goslim_goa:GO:0008150 goslim_goa:GO:0009056 goslim_goa:GO:0034641 goslim_goa:GO:0043167 goslim_goa:GO:0043226 goslim_goa:GO:0044281 goslim_goa:GO:0051186 OTTP:OTTMUSP00000019091 OTTT:OTTMUST00000042491 Reactome:R-MMU-1430728 Reactome:R-MMU-70171 Reactome:R-MMU-70326 Reactome:R-MMU-71387 UniParc:UPI0000DBED38
definition	note : transcript_id=ENSMUST00000127058 protein_id : ENSMUSP00000119392 translation : MADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIRE

name
type	STS
link
xref	UniSTS_NUM:273570 UniSTS:PMC86965P4
definition	note : map_weight=1 standard_name : PMC86965P4

name
type	misc_feature
link
xref
definition	note : contig AC161600.6 119910..218929(1)

name	Pklr (ENSMUSG00000041237)
type	misc_RNA
link	VEGA Ensembl MGI
xref	Vega_transcript:OTTMUST00000042493 Vega_transcript:OTTMUST00000042493 MGI_trans_name:Pklr-005 OTTT:OTTMUST00000042493
definition	note : processed_transcript note : transcript_id=ENSMUST00000151591

name	Pklr (ENSMUSG00000041237)
type	misc_RNA
link	VEGA Ensembl MGI
xref	Vega_transcript:OTTMUST00000042492 Vega_transcript:OTTMUST00000042492 MGI_trans_name:Pklr-004 OTTT:OTTMUST00000042492
definition	note : processed_transcript note : transcript_id=ENSMUST00000148097

Polymorphisms
Exon
Sequence

Polymorphisms Report

Target Strain	MSMv4 JF1v3 KJRv1 SWNv1 CHDv1 NJLv1 BLG2v1 HMIv1 BFMv1 PGN2v1

Gene Symbol (Gene ID)	Pklr (ENSMUSG00000041237)
Transcript ID	ENSMUST00000127058

Reports
substitution
cSNPs	0
Insertion	8
Deletion	11
SNPs	-1kb 89132027(c.-5289C>T), 89132083(c.-5233T>C), 89132177(c.-5139A>C), 89132184(c.-5132C>A), 89132207(c.-5109C>T), 89132330(c.-4986A>G), 89132368(c.-4948G>T), 89132428(c.-4888C>T), 89132436(c.-4880C>T), 89132453(c.-4863G>T), 89132546(c.-4770C>T), 89132625(c.-4691A>G), 89132631(c.-4685A>G), 89132697(c.-4619A>G), 89132709(c.-4607G>T), 89132730(c.-4586G>A), 89132737(c.-4579A>G), 89132799(c.-4517T>C), 89132965(c.-4351C>T), 89132992(c.-4324C>T), 89133018(c.-4298A>G), 89133031(c.-4285A>G), 89133043(c.-4273T>G), 89133103(c.-4213A>G), 89133244(c.-4072G>C), 89133400(c.-3916G>A), 89133538(c.-3778G>T), 89133623(c.-3693C>T), 89133659(c.-3657G>A), 89133730(c.-3586C>G), 89133805(c.-3511C>T), 89133921(c.-3395A>C), 89133975(c.-3341T>C), 89134048(c.-3268T>C), 89134081(c.-3235T>C), 89134236(c.-3080A>G), 89134251(c.-3065G>T), 89134253(c.-3063C>T), 89134386(c.-2930T>A), 89134439(c.-2877A>G), 89134517(c.-2799A>G), 89134550(c.-2766A>C), 89134711(c.-2605C>T), 89134712(c.-2604A>G), 89134717(c.-2599C>T), 89134811(c.-2505T>G), 89134828(c.-2488G>A), 89134930(c.-2386T>C), 89134965(c.-2351A>T), 89134966(c.-2350C>G), 89134983(c.-2333C>T), 89135005(c.-2311T>C), 89135126(c.-2190T>C), 89135150(c.-2166A>G), 89135207(c.-2109C>T), 89135220(c.-2096T>C), 89135947(c.-1369G>A), 89136006(c.-1310G>A), 5'UTR CDS 3'UTR 89136614(c.-97A>T), INTRON 89136691(c.-93+73G>A), 89136709(c.-93+91C>T), 89136711(c.-93+93C>T), 89136840(c.-93+222A>G), 89137210(c.-92-14C>T), 89137439(c.91+33G>A), 89137515(c.91+109A>T), 89137597(c.91+191C>T), 89137623(c.91+217C>A), 89137857(c.91+451A>G), 89138071(c.91+665T>C), 89138096(c.91+690A>C), 89139000(c.91+1594G>A), 89139024(c.91+1618C>T), 89139069(c.91+1663T>C), 89139265(c.91+1859T>G), 89139538(c.92-1777C>T), 89139642(c.92-1673A>C), 89140167(c.92-1148G>A), 89140981(c.92-334G>A), 89141236(c.92-79T>G), 89141286(c.92-29G>A), +1kb 89141541(c.2G>A), 89141547(c.8A>G), 89141610(c.71C>T), 89141718(c.179C>T), 89141813(c.274T>C), 89141822(c.283G>A), 89142273(c.734G>A), 89142796(c.1257C>T), 89143148(c.1609G>A), 89143834(c.2295T>C), 89143845(c.2306C>T), 89143853(c.2314G>A), 89144282(c.2743G>A), 89144509(c.2970T>C), 89144641(c.3102T>C), 89144991(c.3452A>G), 89145078(c.3539C>G), 89145147(c.3608G>T), 89145447(c.3908G>A), 89145612(c.4073C>T), 89145693(c.4154G>C), 89145696(c.4157C>A),
Insertions	-1kb 89132575 (c.-4741_-4740insC), 89133691 (c.-3625_-3624insAGA), 89135805 (c.-1511_-1510insG), 89135909 (c.-1407_-1406insATC), 5'UTR CDS 3'UTR INTRON 89137571 (c.91+174_91+175dupTT), 89139182 (c.91+1785dupT), 89141298 (c.92-15dupG), 89141482 (c.184-23_184-19dupCTCTC), +1kb
Deletions	-1kb 89132940 (c.-4375_-4369delGAGACCG), 89134442 (c.-2873delC), 89134739 (c.-2576_-2574delCTG), 5'UTR CDS 3'UTR INTRON 89136834 (c.-93+217_-93+220delTTGA), 89138020 (c.91+623delA), 89138873 (c.91+1468delT), 89138892 (c.91+1501_91+1504delAAAT), 89138906 (c.91+1501_91+1504delAAAT), 89140505 (c.92-774_92-767delACACACAC), +1kb 89144408 (c.2870_2871delAA), 89146051 (c.*4513delT),
coding sequence substitutions
premature termination by the nucleotide substitution	0
synonymous num	0
non-synonymous num	0
synonymous substitutions
non-synonymous substitutions
B6 transcript (ENSMUST00000127058)	MADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSH EYHAESIANIRE
MSMv4 transcript	MADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSH EYHAESIANIRE
homology	100.00 (72 / 72)

Exon Detail Report

Target Strain	MSMv4 JF1v3 KJRv1 SWNv1 CHDv1 NJLv1 BLG2v1 HMIv1 BFMv1 PGN2v1

Gene Symbol (Gene ID)	Pklr (ENSMUSG00000041237)
Transcript ID	ENSMUST00000127058

No.	Exon / Intron	Start	End	Start Phase	End Phase	Length	Sequence
	5' upstream sequence						..........GATTTCTGCGTTCGAGGCCAGCCTGGTCTACACAGAGAAACCCTGTCTAG AAGAGAAAAGGAAAGGAAAGGAAAGGGAAGGGAAGGGAAGGGAAGGGAAGGGAAGGGAAG GGAAGGGAAGGGAAGGGAAGGGAAGGGAAGGGAAGAGAAGAGAAGAGAAGAGAAGAGAAG AGAAGAGAAGAGAAGAGAAGAGAAGAGAAGAGAAGAGAAGAGAAGAGAAGAGAAAAAAAA GTTCCTCCCTCTTTTCCACAATCTAGTCCCCACATTCAAGCTCTTGCTCTGAGAATATAC CTAAGATTCTTGTCAATAAAATACAAAGAGAAAAGGATTGTATCACTGGCGATGAACTAG TCTCTATTGAAGCTGATGAACTGACAGTATGAATGGACTAAAAATTGACCAGGAAAAACG GATGACCTAGGGGAAGGAAAGATGTGGGGACTGACAACCGACAGCCCTCCAGAAGGGACT CTGTGTGGGGATGGGGCTGCCTACTGGGTGTGCCTCTTTTCTATTCTCTGGCTCCTGCAG ATAAGACCAGCAGTTAGGGTACACTCTCCTCCCAGTCTGTGGTTCTTGCAGCCCCAGTCC CACACTTTGGAAGCATGTCTGTCCAAGAGAACGAGCTACCCCAGCAGCTCTGGCCCTGGA TCTTTAAGTCCCAAAAAGACTTAGCAAAGTCTGCTTTAAGTGGGGCTCCAGGAGGTAAGA AGAGGAAGGGAAGCCACTGAACAGAGAGGAGAATTAGGGTAGAATCAGTGTTGGGGGTGG AGGCCTTGGGGGAAGGATGCCCACTACAGCCTCTGTTAAATTTGATTTGAGCCTTTGATC CAGGCTCTGCAGACAGGCCAAAGGGGATCCGGCAGCATGGACGCCACGGGGCACTCCCGT GGTTCCTGGACTCTGGCCCCCAGTGTACAAGGCTTCCATTGGCAAGAGAGATGCTAGCTG GTTATACTTTAACCAGGACTGATCTCGTCTGTGCCAGGCCCCATCCCACT
1	EXON 1	89,136,579	89,136,618	-	-	40	GACAAAGGCAGAGTATAAAGCAGACCCACAGACACTGCAG
	INTRON 1 - 2	89,136,619	89,137,223			605	GTACGCAGCAGTATGGAAGGTGCTC..........GATCCTGAGTCTCCATCTACCGCAG
2	EXON 2	89,137,224	89,137,406	-	1	183	GGCCAGCAGGATACCTGAGACGTGCCAGTGTGGCCCAGCTGACCCAGGAGCTGGGCACTG CCTTCTTCCAGCAGCAGCAACTGCCCGCAGCTATGGCGGACACCTTCCTGGAACACCTCT GCCTTCTGGATATCGACTCAGAGCCTGTGGCCGCTAGGAGCACCAGCATCATTGCCACCA TCG
	INTRON 2 - 3	89,137,407	89,141,314			3,908	GTAAGACCACCCAACCCTGGGCCGC..........TTTCTTAGTGGCTCTCTGGTTCCAG
3	EXON 3	89,141,315	89,141,406	1	0	92	GGCCGGCGTCACGCTCTGTGGACCGCCTCAAGGAGATGATCAAGGCAGGGATGAACATTG CACGACTCAACTTCTCCCATGGCTCCCATGAG
	INTRON 3 - 4	89,141,407	89,141,505			99	GTGTGGGGAAGTCGTGGAGGGCGGA..........TGCTCTCTCTCTCTCTCACTGCTAG
4	EXON 4	89,141,506	89,141,539	0	-	34	TACCATGCAGAGTCCATCGCCAACATTCGGGAGG
	3' upstream sequence						CAGCTGAGAGCTTTGCAACCTCCCCACTCAGCTACAGACCCGTGGCCATCGCCCTGGACA CCAAGGGTCCTGAGATACGCACTGGAGTCCTGCAGGGGGTGAGAAGCAAGCCTCTGTCTG GGGCCTGGAGGAGTGTGAGAGCCCTGGAGAGGGAGAGAGGGTCAGCACTGCTCAGGGCTC AGCTGTGAAACTCAGGCCTCTCTGCCCATCCCACCCCCTCCAGGGTCCAGAGTCGGAGGT GGAAATTGTGAAGGGTTCACAGGTGCTGGTGACCGTGGATCCAAAGTTCCGGACAAGGGG CGATGCAAAGACAGTGTGGGTGGACTACCACAATATCACCCAGGTCGTTGCAGTGGGGGG CCGCATCTACATTGACGACGGGCTCATCTCCTTAGTGGTGCGGAAAATTGGTACAGAAAT GCTTTCTGATCTTATGAGGCGCCCCCAAAATGGGTCACTTTCTCTTCCTTTGGGTTTCTA TGTTCCATCTGCTCTAGACCACCCACACCGTCCCCTAGCAGTATCTGCTTCCCCACCTGG CCTAGTGGTCCCTGCTGTCATCCTGGGTTGAGGCTGGGCATTTGAGAATCCAAGCTTAAG AGCTCTCTCTGCCATGCCTATATCCCGGCTCAGTCTTGGCAGACACTGGCTCTTTTATAC CTGCAGGCCCAGAGGGACTGGTGACCGAAGTGGAACACGGTGGTTTCTTGGGCAACAGGA AGGGTGTGAACTTACCAAATGCCGAGGTGGACCTGCCTGGGCTATCAGAGCAAGATCTTT TGGATCTGCGCTTCGGGGTGGAGCATAATGTGGACATCATCTTTGCCTCCTTTGTACGAA AAGCCAGTGATGTGGTGGCAGTCCGAGATGCCCTAGGGCCAGAAGGACGGGGCATCAAAA TTATCAGCAAAATCGAGAACCATGAAGGCGTGAAGAAGTGAGGCTTGGTCTTTGGTTCCG TCAGCCCTCTCCCTTTCTTTGCCCCTCTTGTGCATGCTAT..........

Sequence Detail Report

Gene Symbol (Gene ID)	Pklr (ENSMUSG00000041237)
Transcript ID	ENSMUST00000127058

		SNP Information
Strain :
Sequence Retrieve :
Exon translate : CDS Start ( 1 ) - End ( 72 ) -
Strand :	forward reverse
Show sequence :	nucleotide amino acid
Color information