| definition |
GO_component : GO:0005737 - cytoplasm [Evidence IDA]; GO:0005829 - cytosol [Evidence IDA]; GO:0005622 - intracellular [Evidence IEA]; GO:0016020 - membrane [Evidence IDA]; GO:0005942 - phosphoinositide 3-kinase complex [Evidence TAS]; GO:0035030 - phosphoinositide 3-kinase complex, class IA [Evidence ISS]
GO_function : GO:0043125 - ErbB-3 class receptor binding [Evidence ISS]; GO:0005158 - insulin receptor binding [Evidence ISS]; GO:0043560 - insulin receptor substrate binding [Evidence IPI]; GO:0005159 - insulin-like growth factor receptor binding [Evidence ISS]; GO:0016301 - kinase activity [Evidence IEA]; GO:0016303 - phosphatidylinositol 3-kinase activity [Evidence TAS]; GO:0035014 - phosphoinositide 3-kinase regulator activity [Evidence ISS] [Evidence IEA]; GO:0005515 - protein binding [Evidence IPI]
GO_process : GO:0030183 - B cell differentiation [Evidence IMP]; GO:0008286 - insulin receptor signaling pathway [Evidence ISS]; GO:0048009 - insulin-like growth factor receptor signaling pathway [Evidence ISS]; GO:0007242 - intracellular signaling cascade [Evidence IEA]; GO:0043066 - negative regulation of apoptosis [Evidence IDA]; GO:0046854 - phosphoinositide phosphorylation [Evidence ISS]; GO:0006468 - protein amino acid phosphorylation [Evidence IDA]; GO:0007165 - signal transduction [Evidence IEA]
codon_start : 1
note : isoform 2 is encoded by transcript variant 2
product : phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 isoform 2
protein_id : NP_001070963.1
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