definition |
GO_component : GO:0005783 - endoplasmic reticulum [Evidence IEA]; GO:0016021 - integral to membrane [Evidence IEA]; GO:0016020 - membrane [Evidence IEA]
GO_function : GO:0005524 - ATP binding [Evidence IEA] [Evidence ISS]; GO:0003824 - catalytic activity [Evidence IEA]; GO:0016891 - endoribonuclease activity, producing 5'-phosphomonoesters [Evidence IEA]; GO:0016787 - hydrolase activity [Evidence IEA]; GO:0016301 - kinase activity [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence ISS] [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]; GO:0000166 - nucleotide binding [Evidence IEA]; GO:0004674 - protein serine/threonine kinase activity [Evidence ISS] [Evidence IEA]; GO:0016740 - transferase activity [Evidence IEA]
GO_process : GO:0006915 - apoptosis [Evidence IEA]; GO:0007050 - cell cycle arrest [Evidence IDA]; GO:0006917 - induction of apoptosis [Evidence IDA]; GO:0006397 - mRNA processing [Evidence IEA]; GO:0006468 - protein amino acid phosphorylation [Evidence ISS]; GO:0006355 - regulation of transcription, DNA-dependent [Evidence IEA]; GO:0006950 - response to stress [Evidence IMP]; GO:0006986 - response to unfolded protein [Evidence IEA]; GO:0006350 - transcription [Evidence IEA]; GO:0006987 - unfolded protein response, activation of signaling protein activity [Evidence ISS]
codon_start : 1
note : inositol-requiring 1 (Yeast homologue); inositol-requiring 1 beta
product : endoplasmic reticulum (ER) to nucleus signalling 2
protein_id : NP_036146.2
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